Xilio Therapeutics, Inc. is a clinical-stage biotechnology firm dedicated to crafting immunotherapies aimed at strengthening the immune systems of cancer patients. A key part of their pipeline is XTX101, a tumor-selective anti-CTLA-4 monoclonal antibody that is currently undergoing Phase 1/2 clinical trials for various solid tumors. The company also develops a range of cytokine programs, including XTX202 (a modified IL-2), XTX301 (an IL-12 product candidate), and XTX401 (an IL-15 product candidate). These cytokine therapies are ingeniously engineered with a protein domain that keeps them inactive until proteases specific to the tumor microenvironment (TME) cleave this mask, thereby initiating their therapeutic activity. Xilio Therapeutics, Inc. was founded in 2016 and is based in Waltham, Massachusetts.
| Metric | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|
| Revenue | $6.34M | N/A | N/A | N/A | N/A | N/A |
| Cost of Revenue | N/A | N/A | N/A | $1.50M | $1.06M | $240.00K |
| Gross Profit | $6.34M | N/A | N/A | $-1.50M | $-1.06M | $-240.00K |
| Gross Margin | 100.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
| Operating Expenses | $66.93M | $79.13M | $89.15M | $73.55M | $53.50M | $18.79M |
| Operating Income | $-60.58M | $-79.13M | $-89.15M | $-75.04M | $-54.56M | $-19.03M |
| Operating Margin | -954.95% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
| Net Income | $-58.24M | $-76.40M | $-88.22M | $-75.80M | $-55.22M | $-17.31M |
| Net Margin | -918.05% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
| EPS (Basic) | $-1.09 | $-2.78 | $-3.19 | $-2.72 | $-2.01 | $-0.06 |
| EBITDA | N/A | N/A | N/A | N/A | N/A | N/A |
| Stock Option Compensation Expense | N/A | N/A | N/A | N/A | N/A | N/A |
| Price To Earnings Ratio | N/A | N/A | N/A | N/A | N/A | N/A |
| Price To Sales Ratio | N/A | N/A | N/A | N/A | N/A | N/A |
| Shares Outstanding | N/A | N/A | N/A | N/A | N/A | N/A |
| Market Capitalization | N/A | N/A | N/A | N/A | N/A | N/A |