Pliant Therapeutics, Inc. is a biopharmaceutical company in the clinical development stage, dedicated to discovering, advancing, and bringing to market innovative therapies for fibrotic and related diseases across the United States. Its flagship investigational product, PLN-74809, is an orally administered, small-molecule, dual-selective inhibitor targeting both avĂź6 and avĂź1 integrins, which is currently progressing through three distinct Phase 2a clinical trials. The company's pipeline also includes PLN-1474, a small-molecule selective inhibitor of avĂź1, which has successfully completed its Phase 1 clinical assessment for treating liver fibrosis associated with nonalcoholic steatohepatitis (NASH). Furthermore, Pliant is nurturing two additional integrin-based initiatives in preclinical development: one focused on oncology, and another involving an allosteric agonistic monoclonal antibody designed to act upon an undisclosed integrin receptor for the treatment of various muscular dystrophies, including Duchenne muscular dystrophy. Founded in 2015, Pliant Therapeutics, Inc. maintains its corporate headquarters in South San Francisco, California.
| Metric | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|
| Revenue | N/A | $1.58M | $9.69M | $7.57M | $41.82M | $57.05M | N/A | N/A |
| Cost of Revenue | N/A | N/A | N/A | N/A | N/A | N/A | $666.00K | N/A |
| Gross Profit | N/A | $1.58M | $9.69M | $7.57M | $41.82M | $57.05M | $-666.00K | N/A |
| Gross Margin | 0.00% | 100.00% | 100.00% | 100.00% | 100.00% | 100.00% | 0.00% | 0.00% |
| Operating Expenses | $228.37M | $185.72M | $136.88M | $105.11M | $83.46M | $58.28M | $30.25M | $18.35M |
| Operating Income | $-228.37M | $-184.15M | $-127.20M | $-97.53M | $-41.65M | $-1.23M | $-30.91M | $-18.35M |
| Operating Margin | 0.00% | -11654.75% | -1313.37% | -1288.10% | -99.59% | -2.16% | 0.00% | 0.00% |
| Net Income | $-210.30M | $-161.34M | $-123.32M | $-97.26M | $-41.53M | $-631.00K | $-30.28M | $-20.62M |
| Net Margin | 0.00% | -10211.14% | -1273.32% | -1284.51% | -99.32% | -1.11% | 0.00% | 0.00% |
| EPS (Basic) | $-3.47 | $-2.75 | $-2.94 | $-2.71 | $-1.17 | $0.01 | $-1.83 | $-25.67 |
| EBITDA | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Stock Option Compensation Expense | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Price To Earnings Ratio | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Price To Sales Ratio | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Shares Outstanding | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Market Capitalization | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |